- Profile - Drugs for Neglected Diseases initiative (DNDi)

Essentials of the Organization

Established in 2003 in Geneva. DNDi develops and delivers drugs and treatments for neglected disease in collaboration with 8 regional offices worldwide and over 200 industrial, governmental and academic partners.

Honors and Awards

2008 Goodwin Award
2008 Société de Pathologie Exotique Golden Medal
2012 BBVA Foundation
2013 The Rockefeller Foundation
2013 Carlos Slim Foundation
2014 FINEP Award for Innovation
2014 Corporate Social Responsibility Alliance Excellence Award
2017 Prix 2017 de l’Innovation
2018 Anne Maurer-Cecchini Award
2020 Else Kroner Fresenius Award for Development Cooperation in Medicine
2020 Grand Prix, WHO Health for All Film Festival
2020 Golan Christie Taglia Patient Impact Philanthropy Award
2021 French National Order of Merit
2020-2021 Prince Mahidol Award
2021 Prix Galien Africa
2023 Princess of Asturias Award for International Cooperation

Major Publications

The publications listed below represent a selection of DNDi’s extensive research on sleeping sickness, with a focus on Access/Implementation.

Articles

1. Development and introduction of fexinidazole into the Global Human African Trypanosomiasis Program. Valverde Mordt O, Tarral A, Strub-Wourgaft N. The American Journal of Tropical Medicine and Hygiene 2022; tpmd211176.
2. Latest advances in control of sleeping sickness: Towards elimination. Valverde Mordt O. Bulletin of the Netherlands Society for Tropical Medicine and International Health 2020:6-8
3. How clinical research can contribute to strengthening health systems in low resource countries. Mbo F, Mutombo W, Ngolo D, Kabangu P, Valverde Mordt O, Strub-Wourgaft N, Mwamba E. Tropical Medicine and Infectious Diseases 2020, 5(48)
4. Registering new drugs for low-income countries: The African challenge. Moran M, Strub-Wourgaft N, Guzman J, Boulet P, Wu L, Pecoul B. PLos Medicine 2011, 8(2). E1000411
5. NECT is next: Implementing the new drug combination therapy for Trapanosoma brucei gambiense sleeping sickness. Yun O, Priotto G, Tong J, Flevaud L, Chappuis F. PLoS Negl Trop Dis, 2010, 4(5) :e720.

Conference Presentation

1. ISNTD d3 (June 29, 2022) Disease focus: sleeping sickness, de-risking discovery through partnerships and driving sustainability through access. Webinar including Florent Mbo and François Bompart.
2. EDCTP Forum (November 7, 2023) Poster number 580 on Capacity development to facilitate the delivery and uptake of a new medical intervention: fexinidazole oral treatment for the elimination of human African trypanosomiasis with DNDi authors Florent Mbo, Olaf Valverde Mordt, Digas Ngolo, Albert Nyembo, Alphonsine Bilonda.

Textbooks/Miscellaneous

1. Human African trypanosomiasis (sleeping sickness): The road to elimination revisited-achievements and remaining challenges